Greetings,
I thought I was lucky but at 35,000 and just after getting home from a 2400 mile trip around Lake Superior my 2009 S/E Roadglide ate a lifter. At least it waited until I got home to self destruct. No internal mods, consistent Redline oil changes and mostly two up touring. It did have a Master-Tune and a 30 tooth sprocket.
Well what's a boy to do. Had the 117 kit installed while it was apart. Hoping the milder cam and the S&S lifters I used will keep it alive and dependable for at least 30,000 more. I love my orange beast and plan to keep it.
Having worked in several dealerships I can say that it seems to be hit or miss with the Twin Cams. I do believe that there were several design and or manufacturing flaws inherent with all Twin Cams but really present on the 110's, ie, tensioners, compensators, lifters, God awful valve train noise, crank issues, etc. I also believe that Mother HD knew about all these issues and just turned a blind eye.
Do love my 2009 S/E Roadglide though and I plan on keeping her fit and running.

SteveM