Odd with the PC V and autotune, you have a complete backup system in the original HD ECM. If the PC V fails (which I've never heard of one failing), remove it from the harness takes ten minutes if your slow. The HD ECM will run in the failed mode and "get you home", it can't sense the WB sensors and thus thinks the NB has failed and sets the AFR at a very low value (like 12). Bike runs rich but will run just fine.
Regarding the TTS, seems to be a very good solution but we had two replaced with the PC V and autotune. Think it was more of the map than the product, but we can all say that. I had a SSERT and spent too many dollars and time to have a crappy running bike. I switched to the PC V myself, no tune and I have over 11000 on the bike and would never switch. Bike runs cool and I get great mileage (42 with two up over 1000 miles). Power is excellent and I can make changes without going to the "dyno" man.
to each his own but I will never go back.
Also, In would wonder why HD has "slow throttle response built in" and Mastertune takes it out. In would suspect it is emissions based and Steve does a great job at making the bike run great.
One of my long time riding buddies has a 09 CVO Roadglide with the PC V and autotune and a new 10 96 Ultra that Fullsac fixed up and both are great. However, he has yet to ride the Ultra in the South Texas Heat. He road the bike all the way to Nevada to get it tuned. Sounds good and runs good with Fullsac and TTS.