This has been beat to death if you do a search, but I will give it to you in a nutshell.
Rev Performance EMS--self tuning--just plug it in and it tunes the bike itslef. You send them you ECU and they re-program it and send it back overnigth air--real quick. The system will adjust for exhaust, air cleaner and cam changes without the need for a dyno. Real nice if you want to just install something and ride. Want to change cmas down the road--do it and the system will adjust for you.
The TTS is a good tuning device if you like to play around to try to get that last ounce out of the bike. To do it right, you need a qualified tuner and a dyno. Want to changes cams later---another trip to the tuner and dyno.
I see your avitar has 2 bikes listed---the Rev Perf will go right on to the 09 since it uses the same O2 sensor location. On 2010 and 2011 you will need to either 1. install O2 bungs in the headpipe up by the exhaust ports where your 09 has them and plug the stock ones or 2. switch to an 09 catless headpipe (which is what I did).
The TTS is cheaper to purchase, but once you add in the dyno time you will be right up there with the EMS. Both are good products and will get good results, while going down different paths.
Here is a link to an install on an 05--yours will be slightly different in the wiring since your bike already has O2 sensors, but everything else is the same.
http://www.cvoharley.com/smf/index.php?topic=58189.0