Like B said....Vrod!! The new Nightrod is wicked looking. Some of the C models I've seen with the custom paint are awesome looking bikes, or find her an 06 SE V, but the new Vance and Hines 2 into 1 pipe on it so the exhaust is tighter to the frame on the right side. If you get an 07, they have 5 gallon tanks!! I'm 5'8", with a 29" inseam....I wouldn't say my legs are "thick", but I can sit flat footed on the Vrod without a problem.
The good thing on a V for a woman is that all the weight is low, so upper body strength is not a factor...the "tank" is just an air box as all the fuel is under the seat and behind. The bike only weighs 600 lbs, give or take, and is not top heavy at all...handles well, and has all the power a person could ever need. They have also come out with some nice saddlebags, etc for the bike. Windvest windshield...she'd be good to go!!