Ken...I had a S&W AirLite 38 spl for many years. While it was certainly easy to carry, I did not like shooting it at all. It simply hurt my hand to shoot more than 25-30 rounds through it when practicing, so I sold it. I replaced it with a Sig P238, which is a 380. However, it is even easier to carry than the AirLite (thinner profile), and it is a pleasure to shoot. Very accurate and manageable recoil. With the right kind of bullet, it will get the job done as well as anything. Sig is also about to release the P938, which is a slightly larger version of the P238, only it's going to be a 9mm. Both of those guns are 1911 style, with a single action only trigger.
There is no doubt that a revolver is one of the most reliable weapons ever invented, but for me, I prefer an auto, particularly the 1911 style. A 357 snubbie would be a handful. When the Zombies are trying to get in my house, I'll have 14 chances (7 shot magazines) to get 'em.

, and 18 more with the 380.
For about the same money as the Ruger 357, you could even go with something like a Sig C3 45ACP. With the right IWB holster, it's easy to carry, and very concealable. And it's safe "locked and loaded", if you choose to carry that way. Most self defense shots are in the 5-10' range, and a 45 JHP makes a big ol hole. It's a fun gun to shoot too. With a little practice, and the gun cocked and locked, it becomes second nature to sweep the thumb safety off as you are bringing up the weapon for use. Then you have a very short trigger pull, and BANG!
As far as the laser thing is concerned...my C3 has the Crimson Trace Laser Grips (burl wood) with an on/off switch on the left side grip. It also has regular night sights. On the C3, the grips are very comfortable, and the laser is activated by gripping the gun properly. You don't HAVE to use them, but it's there. Once you get the laser adjusted to the point of impact of the bullet, you can be sure that it will go where the red dot is, regardless of what position you are in...like on your back, side, or behind something for cover. And, your head is not necessarily lined up with the barrel of the gun. For shooting "off the hip", I can see where the laser might come in handy. In a bad situation, it's not real likely that you're going to be able to do a proper stance and grip...and I'd prefer not to let the bad guy/gal get very close to me at all.