Hey Chip
Can you share some more details on the valve guide issue? If I have an issue I need to fix, I'd like to know up front. Besides, if the heads have to come off, all bets are off on what the mods would be. 
JW
Sure!
But first let me say that this was my experience and may or may not apply to anyone else.
At somewhere between 10 and 11K miles on the bike, sometimes when I would run the rpm's up
close to redline it was like I was hitting the rev limiter.
The motor would shut down for about a second then it would miss for a few seconds more.
IMO (and this is hindsight cause then I wasn't smart enough to know what was really happening) what was happening was a valve guide was slipping and holding the valve open just a fraction of a second. Between 11K to 19900 miles this happen 5 times. The fifth time I was on the on ramp to I-77s coming home from the NC HOG Rally. This time it was different. Rolling hard in 4th gear at 4K rpm all of a sudden it happened again. This time there was no confusion, no possible way I was hitting the rev limiter at 4K rpm.
About 5 miles from home I rolled on from a stoplight (not hard but not easy either) and all hell broke loose. Parts clanging, beating and knocking. I pulled over and then got the bike to the Harley shop. Front cylinder exhaust valve guide this time stuck
permanently open. Stuck open and the exhaust valve had no choice but to stick also. Stuck in the open position the exhaust valve hit the intake valve and bent it. Bingo, open cylinder and no more forward motion for the 09.
Having a great dealer they replaced the head and installed (correctly) new valve guides. Based on previous issues with 110 head valve guides they also pulled the rear head and replaced the valve guides in it also.
So now I'm offering an opinion which I'm sure the experts can decide whether it's valid or not. From the same 10 to 11K miles to 19900K miles on the bike I had issues with the lifters. I
now don't believe it was really a total lifter issue by itself, it was a lifter issue based on the valve guide slipping those 6 times in the head causing excessive play in the valve train system. After that rework of the heads at 20K miles I must note that I'm now at 48K miles and it runs well. Of the 4 V twin Harley motors in the garage, the 09 SEUC 110 is the nosiest motor I have. I'm sorry to say but I have learned to live with that.
That experience is why I posted above to Brad that I recommended to replace the stock valve guides in his 110.
Is this an issue for everyone? I don't have a clue.
But for me, if the head is coming off of a 110 of mine I'm having the guides replaced.
Everyone else can make that choice on their own.
SBB