I personally have not tried this with a Harley but I use a PC5/Autotune/LCD-200 setup on two of my personal motors. It works beautifully. One of the motors is pulling about 150 hp out of 1000 cc and the other motor is pulling about 275 hp out of 1500 cc.
I know of very few tuners in the country that I would trust. I have found that the vast majority are clueless how this stuff really works.
Canned tunes get motors started, dynos get it to the track and the real tuning starts there. I know several Indy car and stock car dyno operators. They spend 10s of millions of dollars every year getting their dyno program to duplicate what they see off the track data loggers. I skip that step.
Most everything I use has a version of autotune. I use it, but then I verify it. I will be happy to teach you. Good hardware and software makes it easy. Dynojet makes some cool stuff.
Nobody cares more about your motor than you do.
Andy